the ship itself kept sailing for years afterward under new owners, before eventually being deliberately wrecked for insurance fraud, wild final chapter.
Arthur Conan Doyle (yes, the Sherlock Holmes guy) wrote a fictionalized short story about it that actually made the mystery way more famous than it originally was.
found completely abandoned off Portugal in 1872, fully seaworthy, cargo intact, but zero crew and the lifeboat gone. nobody was ever found. theories range from a panicked false-alarm evacuation to piracy, but it's still an open mystery.
some later research suggests a methanol vapor buildup from the cargo (industrial alcohol) might've spooked the crew into evacuating prematurely, thinking the ship would explode